in
DSM–IV–TR, repeated or continued use of an amphetamine or amphetamine-like substance despite significant substance-related behavioral, physiological, and psychosocial problems, with or without tolerance or characteristic symptoms if use is suspended (see
amphetamine withdrawal). In
DSM–5 and
DSM-5-TR, amphetamine dependence has been combined with
amphetamine abuse into a single disorder, and neither is considered a distinct diagnosis any longer (see
stimulant use disorder). See also
substance dependence.