APA Dictionary of Psychology

Burkitt’s lymphoma

Updated on 03/06/2026
a highly aggressive B-cell non-Hodgkin lymphoma marked by rapid tumor growth and MYC gene translocations. Three clinical forms are recognized: endemic (seen primarily in equatorial Africa and strongly associated with Epstein–Barr virus), sporadic (occurring worldwide in children and adults), and immunodeficiency-associated (linked to conditions such as HIV or post-transplant immunosuppression). Treatment typically involves intensive combination chemotherapy, often with targeted agents. [identified by and named after Denis Parsons Burkitt (1911–1993), British surgeon]
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