the irregular development of a fetus, often discovered via prenatal testing (e.g.,
amniocentesis,
chorionic villus sampling). Some fetal abnormalities have a genetic basis (e.g., Down syndrome); some are caused by maternal behaviors (e.g., fetal alcohol syndrome); and others may have a combination of genetic, nutritional, and environmental causes (e.g., spina bifida and other
neural tube defects). See also
congenital defect.