APA Dictionary of Psychology

an autoimmune disorder causing chronic inflammation of connective tissue and characterized by joint pain, a butterfly-shaped rash on the nose and cheeks, and scaly red patches on the skin. The condition may be limited to the skin, or it may also affect internal organs, such as the heart, lungs, and central nervous system (systemic lupus erythematosus; SLE), and involve neurological abnormalities, such as seizures and psychosis.