n. (pl.mucopolysaccharidoses) any of various metabolic disorders that are marked by excess mucopolysaccharide—glycosaminoglycan, a complex carbohydrate—in the tissues. Certain forms of the disease are associated with intellectual developmental disorder. Mucopolysaccharidoses are classified into several groups identified by Roman numerals (e.g., MPS I, MPS II). See beta-glucuronidase deficiency; Hunter syndrome; Hurler syndrome; Maroteaux–Lamy syndrome; Sanfilippo syndrome.