n. any of a group of drugs that are based on
salicin, a compound obtained from the bark of willow trees (
Salix), and that include salicylic acid and its derivatives. The latter are used as analgesics, antipyretics, and anti-inflammatory agents. They act on both the peripheral and central nervous systems, particularly the thalamus, but also mimic some aspects of the adrenal hormones. The best known member is
aspirin (acetylsalicylic acid), introduced in 1899. Other salicylates include
salicylamide and compounds used in topical formulations for the relief of muscle and joint pain.