a condensed mass of
chromatin that is observed in the nucleus of nondividing
somatic cells of females. It is not observed in the somatic cells of normal males. The substance represents material within the X chromosome that is not involved in somatic-cell metabolism. The presence of sex chromatin in somatic cells is generally regarded as proof of the sexual identity of females. Also called
Barr body. See also
chromatin negative;
chromatin positive.